| Compound | Interference reaction | Treatment | ||
|---|---|---|---|---|
| Volumetric titration | Coulometric titration | |||
| Ketones | React with methanol to produce ketal and water | Titrant SS-Z | Solvent KTX | AKX CXU |
| Titrant SS | Solvent CP | |||
| Aldehydes | React with methanol to produce acetal and water React with sulfur dioxide and water | Titrant SS-Z | Solvent KTX | AKX CXU (suitable only for a certain aromatic aldehydes) |
| Titrant SS | Solvent CP | |||
| Lower carboxylic acids | React with methanol to produce ester and water | Titrant SS-Z | Solvent KTX | AKX CXU |
| Titrant SS | Solvent CP | |||
| Amines above pKa 9 | Consume iodine gradually and the end-point becomes unstable | Titrant SS-Z | Solvent KTX | AKX CXU salicylic acid |
| Titrant SS | Solvent CP | |||